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Doniphan is a small unincorporated community in Doniphan County, Kansas, United States. Doniphan is part of the St. Joseph, MO–KS Metropolitan Statistical.
The company that founded the town was organized on November 11, 1854. Doniphan was incorporated in 1869. The community was named for Alexander William Doniphan, a military leader in the Mexican–American War.
A post office was opened in Doniphan on March 3, 1855, and remained in operation until it was discontinued on August 15, 1943.